Prevalence of the Prefoldin Subunit 5 Gene Deletion in Canine Mammary Tumors
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چکیده
منابع مشابه
Prevalence of the Prefoldin Subunit 5 Gene Deletion in Canine Mammary Tumors
BACKGROUND A somatic deletion at the proximal end of canine chromosome 27 (CFA27) was recently reported in 50% of malignant mammary tumors. This region harbours the tumor suppressor gene prefoldin subunit 5 (PFDN5) and the deletion correlated with a higher Ki-67 score. PFDN5 has been described to repress c-MYC and is, therefore, a candidate tumor-suppressor and cancer-driver gene in canine mamm...
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Histological grading is a good parameter to stratify tumors according to their biological aggressiveness. The Elston and Ellis grading method in humans, invasive ductal breast carcinomas and other invasive tumors are routinely used. The aims of this study were classification of mammary gland tumors and also application of a human grading method in canine mammary carcinoma. The samples included ...
متن کاملclassification and grading of canine malignant mammary tumors
histological grading is a good parameter to stratify tumors according to their biological aggressiveness. the elston and ellis grading method in humans, invasive ductal breast carcinomas and other invasive tumors are routinely used. the aims of this study were classification of mammary gland tumors and also application of a human grading method in canine mammary carcinoma. the samples included ...
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a Both authors contributed equally. 15 16 *Corresponding author: Shih-Chieh Chang 17 250, Kuo-Kuang Road, Taichung 40227, TAIWAN 18 Tel.: +886 4 22840404; fax: +886 4 22852016. 19 E-mail address: [email protected] 20 21 Short Title: MMTV-like nucleotide sequences in dogs and cats 22 Copyright © 2010, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights R...
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The incidence and prevalence of paraneoplastic glomerulopathy, especially associated with carcinoma, are a matter of debate and the causal link between cancer and glomerular diseases remains unclear. The aim of this study was to evaluate renal biopsies of selected bitches with spontaneous mammary gland carcinoma. We hypothesized that dogs with mammary carcinomas would show histologic evidence o...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2015
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0131280